A software tool supporting prediction of tumor, stroma and immune cell admixture in bulk ovarian cancer tissue collections using protein-level abundance data.
Welcome to ProteoMixture, established by the Women’s Health Integrated Research Center (WHIRC) at Inova Health System. This tool allows users to interrogate protein abundance data and download tumor, immune and stromal scores. Description of the high grade serous ovarian cancer (HGSOC) tissue samples and methods for prioritizing cell type protein signatures can be found in our manuscript titled “ProteoMixture: A Cell Type Deconvolution Tool for Bulk Tissue Proteomics Data” by Pang-ning Teng, Joshua P Schaaf, Tamara Abulez, Brian L Hood, Katlin N Wilson, Tracy J Litzi, Kelly A Conrads, Allison L Hunt, Victoria Olowu, Julie Oliver, Fred S Park, Marshe Edwards, AiChun Chiang, Praveen-Kumar Raj-Kumar, Christopher M Tarney, Kathleen M Darcy, Neil T Phippen, George L Maxwell, Thomas P Conrads, and Nicholas W Bateman, preprint on bioRxiv July 29, 2023 (https://doi.org/10.1101/2023.07.27.550810). Please contact Dr. Nicholas W. Bateman (firstname.lastname@example.org), Women’s Health Integrated Research Center at Inova Health System, 3289 Woodburn Road, Suite 370, Annandale, VA 22003; Tel: 703-207-3362; or Dr. Thomas P. Conrads (email@example.com), 3289 Woodburn Rd., Suite 375, Annandale, VA 22003 for any questions.